{"id":943,"date":"2026-04-10T22:47:44","date_gmt":"2026-04-10T14:47:44","guid":{"rendered":"https:\/\/longevityforesight.com\/?p=943"},"modified":"2026-04-10T22:47:45","modified_gmt":"2026-04-10T14:47:45","slug":"%e5%a4%9a%e5%90%83%e6%9e%9c%e8%94%ac%e6%88%96%e6%88%96%e9%80%9a%e8%bf%87%e8%b0%83%e8%8a%82%e8%82%a0%e9%81%93%e5%be%ae%e7%94%9f%e7%89%a9%e4%bb%a3%e8%b0%a2%e6%9d%a5%e6%8a%97%e8%a1%b0%e8%80%81","status":"publish","type":"post","link":"https:\/\/longevityforesight.com\/?p=943","title":{"rendered":"\u591a\u5403\u679c\u852c\u6216\u6216\u901a\u8fc7\u8c03\u8282\u80a0\u9053\u5fae\u751f\u7269\u4ee3\u8c22\u6765\u6297\u8870\u8001"},"content":{"rendered":"\n<p>\u8870\u5f31\u662f\u4e00\u79cd\u8001\u5e74\u7efc\u5408\u5f81\uff0c\u5176\u7279\u5f81\u662f\u529f\u80fd\u4e27\u5931\u548c\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0\u3002\u8bc6\u522b\u8870\u5f31\u98ce\u9669\u4eba\u7fa4\u5bf9\u4e8e\u6709\u6548\u7684\u9884\u9632\u5e72\u9884\u81f3\u5173\u91cd\u8981\u3002\u672c\u7814\u7a76\u65e8\u5728\u63a2\u8ba8\u4e24\u4e2a\u610f\u5927\u5229\u7eb5\u5411\u961f\u5217\u4e2d\u8840\u6d46\u9a6c\u5c3f\u9178\u6d53\u5ea6\u4e0e\u8870\u5f31\u4e4b\u95f4\u7684\u5173\u8054\u3002\u91c7\u7528\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u9a8c\u8bc1\u7684\u8d28\u8c31\u6cd5\u5bf9\u6765\u81ea InCHIANTI\uff08n = 534\uff1b55.4% \u4e3a\u5973\u6027\uff1b\u5e74\u9f84 \u226565 \u5c81\uff0c\u5206\u522b\u4e8e 1998 \u5e74\u30012002 \u5e74\u30012004 \u5e74\u548c 2008 \u5e74\u8fdb\u884c\u968f\u8bbf\uff09\u548c InveCe.Ab\uff08n = 912\uff1b53.8% \u4e3a\u5973\u6027\uff1b\u5e74\u9f84 \u226570 \u5c81\uff0c\u5206\u522b\u4e8e 2010 \u5e74\u30012012 \u5e74\u30012014 \u5e74\u548c 2018 \u5e74\u8fdb\u884c\u968f\u8bbf\uff09\u961f\u5217\u7684\u53c2\u4e0e\u8005\u7684\u8840\u6d46\u6837\u672c\u4e2d\u7684\u8840\u6d46\u9a6c\u5c3f\u9178\u8fdb\u884c\u5b9a\u91cf\u5206\u6790\u3002\u6240\u6709\u53c2\u4e0e\u8005\u5728\u57fa\u7ebf\u65f6\u5747\u65e0\u8870\u5f31\u75c7\u72b6\u3002\u672c\u7814\u7a76\u901a\u8fc7\u4e24\u79cd\u4e0d\u540c\u7684\u5206\u7c7b\u65b9\u6cd5\u5b9a\u4e49\u8870\u5f31\uff1a\u8870\u5f31\u6307\u6570\uff08FI\uff09\u548c\u8870\u5f31\u8868\u578b\uff08FP\uff09\u3002\u91c7\u7528\u7ebf\u6027\u6df7\u5408\u6a21\u578b\u8bc4\u4f30\u4e86\u4e24\u4e2a\u961f\u5217\u4e2d\u9a6c\u5c3f\u9178\u4e0e\u8870\u5f31\u6307\u6570\u4e4b\u95f4\u7684\u7eb5\u5411\u5173\u8054\uff0c\u5e76\u6821\u6b63\u4e86\u6027\u522b\u3001\u5e74\u9f84\u3001\u6559\u80b2\u7a0b\u5ea6\u3001\u80be\u529f\u80fd\u3001\u809d\u529f\u80fd\u548c\u4f53\u91cd\u6307\u6570\u7b49\u56e0\u7d20\u3002\u4e2d\u4ecb\u5206\u6790\u63a2\u8ba8\u4e86\u9a6c\u5c3f\u9178\u5728\u6c34\u679c\u548c\u852c\u83dc\u6444\u5165\u91cf\u4e0e\u8870\u5f31\u5173\u7cfb\u4e2d\u7684\u4e2d\u4ecb\u4f5c\u7528\u3002\u5728\u4e24\u9879\u7814\u7a76\u4e2d\uff0c\u865a\u5f31\u53c2\u4e0e\u8005\uff08\u4ee5\u865a\u5f31\u6307\u6570FI\u8bc4\u4f30\uff09\u7684\u9a6c\u5c3f\u9178\u6d53\u5ea6\u4e2d\u4f4d\u6570\u5747\u663e\u8457\u4f4e\u4e8e\u975e\u865a\u5f31\u53c2\u4e0e\u8005\uff1a(i) InCHIANTI\u7814\u7a76\uff1a2004\u5e74\u968f\u8bbf\u65f6\uff0c\u975e\u865a\u5f31\u7ec4\u4e3a1.59 (Q1 &#8211; Q3 , 0.99-2.74) \u03bcg\/ml\uff0c\u865a\u5f31\u7ec4\u4e3a1.18 (0.75-1.88) \u03bcg\/ml\uff1b2007\u5e74\u968f\u8bbf\u65f6\uff0c\u975e\u865a\u5f31\u7ec4\u4e3a1.44 (0.87-2.50) \u03bcg\/ml\uff0c\u865a\u5f31\u7ec4\u4e3a1.12 (0.63-1.99) \u03bcg\/ml\uff1b(ii) InveCe.Ab\u7814\u7a76\uff1a2018\u5e74\u968f\u8bbf\u65f6\uff0c\u975e\u865a\u5f31\u7ec4\u4e3a2.19 (1.26-3.92) \u03bcg\/ml\uff0c\u865a\u5f31\u7ec4\u4e3a1.81 (0.87-3.65) \u03bcg\/ml\u3002\u672a\u53d1\u73b0\u7edf\u8ba1\u5b66\u610f\u4e49\u4e0a\u7684\u663e\u8457\u5dee\u5f02\u3002\u6a2a\u65ad\u9762\u7814\u7a76\u89c2\u5bdf\u5230\u9a6c\u5c3f\u9178\u4e0e\u4f53\u5f31\uff08FP\uff09\u4e4b\u95f4\u5b58\u5728\u5173\u8054\u3002\u7eb5\u5411\u5173\u8054\u5206\u6790\u663e\u793a\uff0c\u8f83\u9ad8\u7684\u8840\u6d46\u9a6c\u5c3f\u9178\u6c34\u5e73\u4e0e\u4f53\u5f31\u98ce\u9669\u964d\u4f4e\u663e\u8457\u76f8\u5173\uff08InCHIANTI\u961f\u5217p = 0.026\uff0cInveCe.Ab\u961f\u5217p = 0.044\uff09\u3002\u7eb5\u5411\u4e2d\u4ecb\u5206\u6790\u8868\u660e\uff0c\u5728\u4e24\u4e2a\u961f\u5217\u4e2d\uff0c\u9a6c\u5c3f\u9178\u5747\u5728\u6c34\u679c\u548c\u852c\u83dc\u6444\u5165\u91cf\u4e0e\u4f53\u5f31\uff08FI\uff09\u4e4b\u95f4\u8d77\u4e2d\u4ecb\u4f5c\u7528\uff08p &lt; 0.05\uff09\u3002\u4f4e\u8840\u6d46\u9a6c\u5c3f\u9178\u6c34\u5e73\u53ef\u80fd\u4f5c\u4e3a\u4f53\u5f31\u7684\u6807\u5fd7\u7269\uff0c\u5e76\u53ef\u80fd\u4e0e\u6c34\u679c\u548c\u852c\u83dc\u6444\u5165\u91cf\u51cf\u5c11\u6709\u5173\u3002<\/p>\n\n\n\n<p>\ud83d\udd17 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41957363\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/41957363\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6765\u81ea NPJ Aging \u7684\u7814\u7a76\u53d1\u73b0\uff0c\u8840\u6db2\u4e2d\u9a6c\u5c3f\u9178\uff08hippuric acid\uff09\u6c34\u5e73\u8f83\u9ad8\uff0c\u4e0e\u8001\u5e74\u4eba\u8870\u5f31\u98ce\u9669\u663e\u8457\u964d\u4f4e\u76f8\u5173\uff08P\u503c\u5747<0.05\uff09\u3002\u8fd9\u9879\u7814\u7a76\u5171\u6d89\u53ca\u8d85\u5343\u540d65\u5c81\u4ee5\u4e0a\u8001\u5e74\u4eba\uff0c\u9996\u6b21\u8bc1\u5b9e\u9a6c\u5c3f\u9178\u662f\u996e\u98df\u5e72\u9884\u4e0e\u8870\u5f31\u4e4b\u95f4\u7684\u5173\u952e\u4ecb\u8d28\u3002\u7531\u4e8e\u9a6c\u5c3f\u9178\u662f\u80a0\u9053\u5fae\u751f\u7269\u4ee3\u8c22\u679c\u852c\u4e2d\u591a\u915a\u7684\u4ea7\u7269\uff0c\u56e0\u6b64\u63d0\u793a\u6211\u4eec\u591a\u5403\u679c\u852c\u6216\u901a\u8fc7\u8c03\u8282\u80a0\u9053\u5fae\u751f\u7269\u4ee3\u8c22\uff0c\u8fdb\u800c\u63d0\u5347\u9a6c\u5c3f\u9178\u6c34\u5e73\uff0c\u53ef\u80fd\u6210\u4e3a\u51cf\u7f13\u8870\u8001\u3001\u7ef4\u62a4\u5065\u5eb7\u5bff\u547d\u7684\u91cd\u8981\u9014\u5f84\u3002 \n<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[14],"tags":[],"class_list":["post-943","post","type-post","status-publish","format-standard","hentry","category-featured"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u591a\u5403\u679c\u852c\u6216\u6216\u901a\u8fc7\u8c03\u8282\u80a0\u9053\u5fae\u751f\u7269\u4ee3\u8c22\u6765\u6297\u8870\u8001 - Longevity Foresight<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longevityforesight.com\/?p=943\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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