{"id":834,"date":"2026-04-03T23:37:57","date_gmt":"2026-04-03T15:37:57","guid":{"rendered":"https:\/\/longevityforesight.com\/?p=834"},"modified":"2026-04-03T23:37:58","modified_gmt":"2026-04-03T15:37:58","slug":"%e6%8a%97%e8%a1%b0%e6%98%8e%e6%98%9f%e8%8d%af%e9%9b%b7%e5%b8%95%e9%9c%89%e7%b4%a0%e7%a0%94%e7%a9%b6%e5%86%8d%e8%bf%9b%e4%b8%80%e6%ad%a5%ef%bc%8ciii-%e6%9c%9f%e4%b8%b4%e5%ba%8a%e6%ad%a3%e5%bc%8f","status":"publish","type":"post","link":"https:\/\/longevityforesight.com\/?p=834","title":{"rendered":"\u6297\u8870\u660e\u661f\u836f\u96f7\u5e15\u9709\u7d20\u7814\u7a76\u518d\u8fdb\u4e00\u6b65\uff0cIII \u671f\u4e34\u5e8a\u6b63\u5f0f\u542f\u52a8"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/longevityforesight.com\/wp-content\/uploads\/2026\/04\/image-21-1024x683.png\" alt=\"\" class=\"wp-image-835\" srcset=\"https:\/\/longevityforesight.com\/wp-content\/uploads\/2026\/04\/image-21-1024x683.png 1024w, https:\/\/longevityforesight.com\/wp-content\/uploads\/2026\/04\/image-21-300x200.png 300w, https:\/\/longevityforesight.com\/wp-content\/uploads\/2026\/04\/image-21-768x512.png 768w, https:\/\/longevityforesight.com\/wp-content\/uploads\/2026\/04\/image-21.png 1140w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u4e9a\u5229\u6851\u90a3\u5927\u5b66&nbsp;<a href=\"https:\/\/www.pharmacy.arizona.edu\/\">R. Ken Coit \u836f\u5b66\u9662\u7684<\/a>\u7814\u7a76\u4eba\u5458\u5c06\u4e8e\u4eca\u5e74\u5f00\u59cb\u4e00\u9879\u53cc\u76f2\u3001\u968f\u673a\u7684 3 \u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc4\u4f30\u4e00\u79cd\u7528\u4e8e\u9884\u9632\u5668\u5b98\u79fb\u690d\u6392\u65a5\u53cd\u5e94\u7684\u836f\u7269\u662f\u5426\u4e5f\u80fd\u63d0\u9ad8\u8001\u5e74\u4eba\u7684\u62b5\u6297\u529b\u548c\u514d\u75ab\u529f\u80fd\u3002<\/p>\n\n\n\n<p>\u8fd9\u9879\u9488\u5bf9\u96f7\u5e15\u9709\u7d20\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u5f97\u4e86\u6821\u53cbR\u00b7\u80af\u00b7\u79d1\u4f0a\u7279\uff08R. Ken Coit\uff091200\u4e07\u7f8e\u5143\u7684\u6148\u5584\u6350\u8d60\u3002\u79d1\u4f0a\u7279\u4e8e1967\u5e74\u6bd5\u4e1a\u4e8e\u836f\u5b66\u9662\uff0c\u51e0\u5341\u5e74\u6765\u4e00\u76f4\u662f\u8be5\u5b66\u9662\u7684\u652f\u6301\u8005\u30022021\u5e74\uff0c\u4ed6\u627f\u8bfa\u6350\u8d605000\u4e07\u7f8e\u5143\u7528\u4e8e\u8bbe\u7acb\u6350\u8d60\u6559\u5e2d\u548c\u5b66\u751f\u5956\u5b66\u91d1\uff0c\u5e76\u7528\u4e8e\u7ffb\u65b0\u79d1\u4f0a\u7279\u836f\u5b66\u4e0e\u5065\u5eb7\u79d1\u5b66\u53f2\u535a\u7269\u9986\u3002&nbsp;<\/p>\n\n\n\n<p>\u201c\u6211\u4eec\u975e\u5e38\u611f\u8c22\u80af\u7684\u6700\u65b0\u6350\u8d60\uff0c\u8fd9\u5c06\u6709\u52a9\u4e8e\u6211\u4eec\u4ee5\u5168\u65b0\u7684\u89c6\u89d2\u5ba1\u89c6\u8870\u8001\u548c\u957f\u5bff\u7684\u610f\u4e49\uff0c\u5e76\u6709\u671b\u4e3a\u66f4\u591a\u4eba\u5e26\u6765\u66f4\u7f8e\u597d\u3001\u66f4\u5145\u5b9e\u7684\u751f\u6d3b\uff0c\u201d\u4e9a\u5229\u6851\u90a3\u5927\u5b66\u6821\u957f\u82cf\u96f7\u4ec0\u00b7\u52a0\u91cc\u6885\u62c9\u8868\u793a\u3002\u201c\u4ed6\u957f\u671f\u4ee5\u6765\u7684\u5173\u6ce8\u548c\u6177\u6168\u6350\u52a9\uff0c\u4f7f\u6211\u4eec\u7684\u836f\u5b66\u9662\u8dfb\u8eab\u5168\u7f8e\u9876\u5c16\u884c\u5217\u3002\u201d<\/p>\n\n\n\n<p>\u957f\u5bff\u79d1\u5b66\u548c\u8870\u8001\u4e00\u76f4\u662f\u4e9a\u5229\u6851\u90a3\u5927\u5b66\u7684\u7814\u7a76\u91cd\u70b9\u3002\u79d1\u4f0a\u7279\u836f\u5b66\u9662\u4e0b\u5c5e\u7684\u79d1\u4f0a\u7279\u957f\u5bff\u4e0e\u795e\u7ecf\u6cbb\u7597\u4e2d\u5fc3\u6210\u7acb\u4e8e2023\u5e74\uff0c\u65e8\u5728\u4fc3\u8fdb\u4fc3\u8fdb\u5065\u5eb7\u8001\u9f84\u5316\u7684\u65b0\u53d1\u73b0\u548c\u7597\u6cd5\u3002\u8be5\u4e2d\u5fc3\u7684\u7814\u7a76\u5de5\u4f5c\u6db5\u76d6\u4e86\u4ece\u589e\u8fdb\u5bf9\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u5e15\u91d1\u68ee\u75c5\u7b49\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u7406\u89e3\uff0c\u5230\u53d1\u73b0\u65b0\u7684\u836f\u7269\u9776\u70b9\uff0c\u4ee5\u53ca\u5f00\u53d1\u80fd\u591f\u5ef6\u7f13\u8870\u8001\u548c\u75be\u75c5\u7684\u7597\u6cd5\u3002<\/p>\n\n\n\n<p>\u79d1\u4f0a\u7279\u836f\u5b66\u9662\u4e34\u65f6\u9662\u957f\u5e03\u83b1\u6069\u00b7\u57c3\u5c14\u65af\u5854\u5fb7\u8868\u793a\uff1a\u201c\u80af\u7684\u6177\u6168\u6350\u8d60\u4f7f\u5f97\u836f\u5b66\u9662\u9996\u4e2a\u7531\u7814\u7a76\u8005\u4e3b\u5bfc\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6210\u4e3a\u53ef\u80fd\u3002\u4ed6\u7684\u6700\u65b0\u6350\u8d60\u5c06\u4e3a\u6211\u4eec\u7684\u7814\u7a76\u4eba\u5458\u63d0\u4f9b\u65b0\u7684\u673a\u4f1a\uff0c\u8ba9\u4ed6\u4eec\u80fd\u591f\u7ee7\u7eed\u6df1\u5165\u4e86\u89e3\u4eba\u7c7b\u5bff\u547d\uff0c\u5e76\u5728\u5f00\u53d1\u5ef6\u7f13\u8870\u8001\u7597\u6cd5\u65b9\u9762\u53d6\u5f97\u65b0\u7684\u8fdb\u5c55\u3002\u201d&nbsp;<\/p>\n\n\n\n<p>\u201c\u96f7\u5e15\u9709\u7d20\u662f\u6211\u4eec\u63d0\u9ad8\u8001\u5e74\u4eba\u62b5\u6297\u529b\u548c\u5065\u5eb7\u5bff\u547d\u7684\u6700\u4f73\u9009\u62e9\uff0c\u201d\u79d1\u4f0a\u7279\u8bf4\u3002\u201c\u591a\u9879\u7814\u7a76\u5df2\u8bc1\u5b9e\uff0c\u96f7\u5e15\u9709\u7d20\u53ef\u4ee5\u63d0\u9ad8\u75ab\u82d7\u6548\u529b\uff0c\u5e76\u6539\u5584\u8001\u5e74\u4eba\u7684\u53e3\u8154\u5065\u5eb7\u3002\u8fd9\u9879\u7814\u7a76\u5c06\u8bc4\u4f30\u4f4e\u5242\u91cf\u96f7\u5e15\u9709\u7d20\u80fd\u5426\u7ef4\u6301\u6216\u6539\u558465\u5c81\u53ca\u4ee5\u4e0a\u4eba\u7fa4\u7684\u8eab\u4f53\u548c\u514d\u75ab\u529f\u80fd\u3002\u201d<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/cdn.uanews.arizona.edu\/s3fs-public\/styles\/az_small\/public\/2026-03\/Bonnie-Lafleur_khp9745-web.jpg.webp?VersionId=8jyxronOkxwGXn82QF.u7mzkPaxr.iVX&amp;itok=KBqxNCo2\" alt=\"\u90a6\u59ae\u00b7\u62c9\u5f17\u52d2\"\/><figcaption class=\"wp-element-caption\">\u90a6\u59ae\u00b7\u62c9\u5f17\u52d2<\/figcaption><\/figure>\n\n\n\n<p>\u636e\u9996\u5e2d\u7814\u7a76\u5458\u3001\u79d1\u4f0a\u7279\u836f\u5b66\u9662\u6559\u6388\u90a6\u59ae\u00b7\u62c9\u5f17\u52d2 (Bonnie LaFleur) \u4ecb\u7ecd\uff0c\u5982\u679c\u8fd9\u9879\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5982\u9884\u671f\u822c\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u7684\u6700\u7ec8\u6279\u51c6\uff0c\u9884\u8ba1\u5c06\u6301\u7eed\u516d\u5e74\u3002\u53c2\u4e0e\u8005\u5c06\u88ab\u968f\u673a\u5206\u914d\u81f3\u96f7\u5e15\u9709\u7d20\u7ec4\u6216\u5b89\u6170\u5242\u7ec4\uff0c\u670d\u7528\u4e24\u5e74\uff0c\u4e4b\u540e\u8fdb\u884c\u4e00\u5e74\u7684\u968f\u8bbf\u3002\u5408\u4f5c\u8005\u5c06\u4e0e\u4e34\u5e8a\u8bd5\u9a8c\u540c\u6b65\u5f00\u5c55\u591a\u9879\u8f85\u52a9\u7814\u7a76\uff0c\u6240\u6709\u8fd9\u4e9b\u7814\u7a76\u7684\u76ee\u6807\u90fd\u662f\u4e3a\u4e86\u6539\u5584\u8001\u5e74\u4eba\u7684\u5065\u5eb7\u548c\u798f\u7949\u3002&nbsp;<\/p>\n\n\n\n<p>\u7814\u7a76\u4eba\u5458\u5c06\u91cd\u70b9\u5173\u6ce8\u4e24\u79cd\u8bc4\u4f30\u96f7\u5e15\u9709\u7d20\u6f5c\u5728\u7597\u6548\u7684\u4e3b\u8981\u65b9\u6cd5\u3002\u7b2c\u4e00\u79cd\u65b9\u6cd5\u662f\u8bc4\u4f30\u8be5\u7597\u6cd5\u5bf9\u8eab\u4f53\u673a\u80fd\u7684\u5f71\u54cd\uff0c\u7279\u522b\u662f\u96f7\u5e15\u9709\u7d20\u662f\u5426\u4f1a\u6539\u53d8\u60a3\u8005\u5411\u8870\u5f31\u72b6\u6001\u8f6c\u53d8\u7684\u8fc7\u7a0b\uff0c\u56e0\u4e3a\u8870\u5f31\u72b6\u6001\u4f1a\u663e\u8457\u5f71\u54cd\u751f\u6d3b\u8d28\u91cf\u3002\u7b2c\u4e8c\u79cd\u65b9\u6cd5\u662f\u8bc4\u4f30\u4e00\u79cd\u540d\u4e3aIL-6\u7684\u708e\u75c7\u6807\u5fd7\u7269\u7684\u6c34\u5e73\uff0cIL-6\u662f\u4e00\u79cd\u4e0e\u591a\u79cd\u5e74\u9f84\u76f8\u5173\u75be\u75c5\uff08\u5305\u62ec\u8870\u5f31\uff09\u76f8\u5173\u7684\u708e\u75c7\u6307\u6807\u3002\u7814\u7a76\u4eba\u5458\u5e0c\u671b\u4e86\u89e3\u96f7\u5e15\u9709\u7d20\u662f\u5426\u80fd\u591f\u964d\u4f4e\u8840\u6db2\u4e2d\u7684IL-6\u6c34\u5e73\u3002&nbsp;<\/p>\n\n\n\n<p>\u201c\u5f53\u6211\u4eec\u63ed\u5f00\u957f\u5bff\u548c\u5065\u5eb7\u8001\u9f84\u5316\u7684\u79d8\u5bc6\u65f6\uff0c\u6211\u4eec\u66f4\u52a0\u610f\u8bc6\u5230\uff0c\u79d1\u5b66\u7684\u627f\u8bfa\u5fc5\u987b\u59cb\u7ec8\u670d\u52a1\u4e8e\u793e\u4f1a\uff0c\u201d\u8d1f\u8d23\u7814\u7a76\u548c\u5408\u4f5c\u7684\u9ad8\u7ea7\u526f\u6821\u957f\u6258\u9a6c\u65af\u00b7\u8fea\u4e9a\u5179\u00b7\u5fb7\u62c9\u9c81\u6bd4\u4e9a (Tom\u00e1s D\u00edaz de la Rubia) \u8868\u793a\u3002&nbsp;&nbsp;\u201c\u5728\u4e9a\u5229\u6851\u90a3\u5927\u5b66\uff0c\u6211\u4eec\u4f5c\u4e3a\u4e00\u6240\u8d60\u5730\u5927\u5b66\u7684\u4f7f\u547d\u9a71\u4f7f\u6211\u4eec\u628a\u79d1\u5b66\u53d1\u73b0\u8f6c\u5316\u4e3a\u4e9a\u5229\u6851\u90a3\u5dde\u4e43\u81f3\u5168\u4e16\u754c\u4eba\u6c11\u7684\u798f\u7949\u3002\u901a\u8fc7\u5927\u80c6\u7684\u8de8\u5b66\u79d1\u8001\u9f84\u5316\u7814\u7a76\uff0c\u6211\u4eec\u6b63\u5728\u5851\u9020\u4e00\u4e2a\u4e0d\u4ec5\u80fd\u591f\u5ef6\u957f\u5bff\u547d\uff0c\u800c\u4e14\u80fd\u591f\u66f4\u5065\u5eb7\u5730\u751f\u6d3b\u7684\u672a\u6765\u3002\u201d<\/p>\n\n\n\n<p>\u201c\u8fd9\u9879\u7814\u7a76\u7684\u6210\u679c\u5c06\u6709\u52a9\u4e8e\u4fc3\u8fdb\u5065\u5eb7\u8001\u9f84\u5316\uff0c\u8fd9\u5173\u7cfb\u5230\u6211\u4eec\u6240\u6709\u4eba\uff0c\u201d\u4e9a\u5229\u6851\u90a3\u5927\u5b66\u57fa\u91d1\u4f1a\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u7ea6\u7ff0-\u4fdd\u7f57\u00b7\u7f57\u5179\u5c3c\u4e9a\u514b\u8868\u793a\uff0c\u201c\u6211\u611f\u8c22\u80af\u518d\u6b21\u5c55\u73b0\u4e86\u6148\u5584\u4e8b\u4e1a\u5728\u63a8\u52a8\u79d1\u5b66\u8fdb\u6b65\u65b9\u9762\u7684\u529b\u91cf\u3002\u201d<\/p>\n\n\n\n<p>\u5728\u79d1\u4f0a\u7279\u5bb6\u65cf\u57fa\u91d1\u4f1a\u53c2\u4e0e\u768430\u4ebf\u7f8e\u5143\u201c\u71c3\u6599\u5947\u8ff9\u201d\u7b79\u6b3e\u6d3b\u52a8\u4e2d\uff0c\u79d1\u4f0a\u7279\u5bb6\u65cf\u57fa\u91d1\u4f1a\u662f\u8be5\u5927\u5b66\u6700\u6177\u6168\u7684\u652f\u6301\u8005\u4e4b\u4e00\uff0c\u81ea2017\u5e74\u4ee5\u6765\u5df2\u627f\u8bfa\u6350\u6b3e\u8d85\u8fc77500\u4e07\u7f8e\u5143\u3002<\/p>\n\n\n\n<p>\ud83d\udd17 <a href=\"https:\/\/news.arizona.edu\/news\/u-launches-rapamycin-clinical-trial-philanthropic-support-alumnus-ken-coit\">https:\/\/news.arizona.edu\/news\/u-launches-rapamycin-clinical-trial-philanthropic-support-alumnus-ken-coit<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e9a\u5229\u6851\u90a3\u5927\u5b66\u836f\u5b66\u9662\u542f\u52a8\u4e86\u4e00\u9879\u7531\u4ebf\u4e07\u5bcc\u7fc1\u6821\u53cbKen Coit\u6350\u8d601200\u4e07\u7f8e\u5143\u8d44\u52a9\u7684\u957f\u5bff\u9879\u76ee\uff0c\u8be5\u9879\u76ee\u4e3a\u53cc\u76f2\u968f\u673aIII\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f30\u96f7\u5e15\u9709\u7d20\u662f\u5426\u80fd\u6539\u558465\u5c81\u53ca\u4ee5\u4e0a\u8001\u5e74\u4eba\u7684\u8eab\u4f53\u97e7\u6027\u548c\u514d\u75ab\u529f\u80fd\u3002 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